James Smyth may refer to:
- Sir James Smyth (English MP) (c. 1621–1681), English Member of Parliament for Exeter and Camelford
- Sir James Smyth, 1st Baronet (c. 1686–1717), Sheriff of Sussex 1714–15
- James Smyth (Irish MP) (c. 1716–1771), Irish Member of Parliament for Antrim and Dundalk
- James Smyth (priest) (1683–1799), Anglican priest in Ireland
- James Carmichael Smyth (physician) (1742–1821), Scottish medical writer and physician to King George III
- Sir James Carmichael-Smyth, 1st Baronet (1779–1838), his son, British colonial administrator
- James Adger Smyth (1837–1920), mayor of Charleston, South Carolina
- Red Smyth (James Daniel Smyth, 1893–1958), American baseball player
- James G. Smyth (fl. mid-20th century), American politician
- Jimmy Smyth (hurler) (1931–2013), Irish hurler
See also
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This disambiguation page lists articles about people with the same name.
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