Fumarylacetoacetic acid (fumarylacetoacetate) is an intermediate in the metabolism of tyrosine. It is formed through the conversion of maleylacetoacetate into fumarylacetoacetate by the enzyme maleylacetoacetate isomerase.[1]
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Preferred IUPAC name
(2E)-4,6-Dioxooct-2-enedioic acid | |
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3D model (JSmol)
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ChemSpider | |
MeSH | Fumarylacetoacetate |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C8H8O6 | |
Molar mass | 200.146 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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See also
editReferences
edit- ^ W. E. Knox and M. LeMay-Knox (1951). "The oxidation in liver of l-tyrosine to acetoacetate through p-hydroxyphenylpyruvate and homogentisic acid". Biochem. J. 49 (5): 686–693. doi:10.1042/bj0490686. PMC 1197578. PMID 14886367.