Frederick William I (German: Friedrich Wilhelm I) may refer to:
- Frederick William I, Duke of Saxe-Weimar (1562–1602)
- Frederick William, Elector of Brandenburg, the "Great Elector" of Brandenburg-Prussia (1620–1688)
- Frederick William I, Duke of Schleswig-Holstein-Sonderburg-Beck (1682–1719)
- Frederick William I of Prussia (1688–1740)
- Frederick William, Elector of Hesse (1802–1875)
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