Francis Popham may refer to:
- Sir Francis Popham (1573–1644), English soldier and colonizer
- Sir Francis Popham (1646–1674), English MP for Bath, grandson of the above
- Francis Popham (died 1734), English MP for Wootton Basset and Chippenham
- Francis Popham (cricketer) (1809–1880), Oxford University cricketer
This disambiguation page lists articles about people with the same name.
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