File:Testosterone levels with 100 to 300 mg per day oral cyproterone acetate and 0.1 mg per day diethylstilbestrol in men.png

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English: Levels of testosterone (ng/dL) during therapy with 100 to 300 mg/day oral cyproterone acetate (CPA) and low-dose oral estrogen in men with prostate cancer. The estrogen used was 0.1 mg/day diethylstilbestrol (DES), which has been described as an "extremely low" dosage. By itself, 3 mg/day DES is able to consistently suppress testosterone levels into the castrate range in men. DES was discontinued at 5 months and reintroduced at 13 months to assess its contribution to suppression of testosterone levels. Levels of testosterone were decreased by about 95% with the combination and by about 61% with cyproterone acetate only.

Source of the values:

  • (December 1988). "The combination of cyproterone acetate and low dose diethylstilbestrol in the treatment of advanced prostatic carcinoma". J. Urol. 140 (6): 1460–5. DOI:10.1016/S0022-5347(17)42073-8. PMID 2973529.

Source for the "extremely low" dosage comment regarding DES:

Date
Source Own work
Author Medgirl131

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current04:47, 22 June 2019Thumbnail for version as of 04:47, 22 June 20191,447 × 1,101 (181 KB)Vanished user 0x8cSXE0x6Improvements.
04:11, 18 December 2018Thumbnail for version as of 04:11, 18 December 20181,454 × 1,099 (182 KB)Vanished user 0x8cSXE0x6User created page with UploadWizard
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