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Summary
| Description |
English: The third CGI of TCF21 contains a promoter that directs transcription of TARID (a lncRNA) in antisense orientation to TCF21. TARID then induces TET protein-dependent DNA demethylation, thus activating TCF21 transcription. This mechanism is regulated by the binding of TARID to the TCF21 promoter, which recruits GADD45A/TDG to direct BER for demethylation. |
| Date | |
| Source | Own work |
| Author | Lh37 |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 04:10, 6 May 2016 | | 1,066 × 745 (197 KB) | Lh37 | Cross-wiki upload from en.wikipedia.org |
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