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Summary
| Description |
English: Eight-week-old mice were intranasally inoculated with 7,000 PFU of rSeV-luc(P-M), rSeV-luc(F-HN), or rSeV-luc(M-F*). Every 24 hours the mice were intraperitoneally injected with luciferin substrate, anesthetized with isoflurane, imaged with a Xenogen IVIS device, and then allowed to recover. Bioluminescence in one experiment is shown on day 2 (A) and day 7 (B) post-infection (p.i.) in 129/SvJ mice infected with rSeV-luc(P-M), rSeV-luc(F-HN), or rSeV-luc(M-F*). The data are displayed as radiance (bioluminescence intensity) on a rainbow log scale with a range of 1×106 (blue) to 1×109 (red) photons/s/cm2/steradian. Red circles indicate regions of interest (ROI) used to calculate the total flux (photons/s) in the nasopharynx, and red rectangles indicate the ROI areas for the trachea and lungs. |
| Date | |
| Source |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131265/ PLoS Pathog. 2011 Jul; 7(7): e1002134. Published online 2011 Jul 7. doi: 10.1371/journal.ppat.1002134 PMCID: PMC3131265 PMID: 21750677 Illumination of Parainfluenza Virus Infection and Transmission in Living Animals Reveals a Tissue-Specific Dichotomy |
| Author | Crystal W. Burke, John N. Mason, Sherri L. Surman, Bart G. Jones, Emilie Dalloneau, Julia L. Hurwitz, and Charles J. Russell |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 20:11, 14 February 2020 | | 400 × 573 (298 KB) | Olgamatveeva | User created page with UploadWizard |
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