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Summary
| Description |
English: Histopathology of usual ductal hyperplasia (UDH) on H&E stain and immunohistochemistry. As seen on higher magnification H&E stain at left, it has the usual irregular "slit-like" lumina. However, this case had almost moderate atypia with somewhat enlarged vesicular nuclei in the periphery, and therefore immunohistochemistry was performed that confirmed UDH: - Estrogen receptor showing heterogeneous positivity, rather than the diffusely positive expression seen in atypical ductal hyperplasia (ADH) - CK 5/6 with a mosaic pattern, predominantly in the central zone, rather than the negative expression seen in ADH - E-cadherin and p120 showing membranous staining, rather than being negative and cytoplasmic, respectively, in lobular carcinoma in situ - Myoepithelial stain (calponin in this case) showing circumferential staining, rather than the absent staining seen in breast cancer.
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.jpg) - Reusing images - Conflicts of interest: None Consent note: Consent from the patient or patient's relatives is regarded as redundant, because of absence of identifiable features (List of HIPAA identifiers) in the media and case information (See also HIPAA case reports guidance). |
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Licensing
 
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This file is made available under the Creative Commons CC0 1.0 Universal Public Domain Dedication. |
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File history
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 19:57, 15 January 2024 | | 4,697 × 4,380 (23.62 MB) | Mikael Häggström | +Atypia |
| 19:56, 15 January 2024 |  | 4,697 × 4,380 (23.87 MB) | Mikael Häggström | Uploaded a work by {{Mikael Häggström|cat=Micrographs of the breast|consent=noid}} from {{Own}} with UploadWizard |
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