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Summary
| Description |
English: FAT and FATP are located on both sides of the bipolar placental cells, and lack of specificity for particular types of fatty acids suggests they may transport all FFAs (nonessential, EFAs, and LCPUFAs) in both directions, i.e., from the mother to the fetus and vice versa, whereas p-FABPpm preferentially sequesters maternal plasma LCPUFAs. Cytoplasmic FABPs may be responsible for the transcytoplasmic movement of FFAs to their sites of esterification, i-oxidation, or fetal circulation via placental basal membranes. VLDL, very low-density lipoproteins; LDL, low-density lipoproteins; PL, placental lipase (pH optima 6.0); PPARk; peroxisome proliferator-activated receptor-k; ACBP, acyl-CoA-binding protein |
| Date | |
| Source | Duttaroy, A.K. Cellular uptake of long-chain fatty acids: role of membrane-associated fatty-acid-binding/transport proteins. Cell. Mol. Life Sci. 57 (2000) 1360–1372 PMID: 11078015, DOI: 10.1007/PL00000621 |
| Author | Asim Kumar Duttaroy |
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| current | 16:49, 2 May 2024 | | 1,190 × 872 (534 KB) | Arnabs89 | Uploaded a work by Asim Kumar Duttaroy from Duttaroy, A.K. Cellular uptake of long-chain fatty acids: role of membrane-associated fatty-acid-binding/transport proteins. Cell. Mol. Life Sci. 57 (2000) 1360–1372 PMID: 11078015, DOI: 10.1007/PL00000621 with UploadWizard |
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