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Summary
| Description |
English: An enzyme binding site that would normally bind substrate can alternatively bind a competitive inhibitor, preventing substrate access. Dihydrofolate reductase is inhibited by methotrexate which prevents binding of its substrate, folic acid. Binding site in blue, inhibitor in green, and substrate in black. (PDB: 4QI9) |
| Date | |
| Source | Own work |
| Author | Thomas Shafee |
| Other versions | For vector version, see File:DHFR methotrexate inhibitor.svg |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 20:53, 4 October 2016 | | 914 × 861 (176 KB) | Cmdrjameson | Compressed with pngout. Reduced by 93kB (34% decrease). |
| 11:35, 6 March 2015 |  | 914 × 861 (269 KB) | Evolution and evolvability | User created page with UploadWizard |
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