Somantadine (INNTooltip International Nonproprietary Name; developmental code name PR 741-976), or somantadine hydrochloride (USANTooltip United States Adopted Name) in the case of the hydrochloride salt, is an experimental antiviral drug of the adamantane family related to amantadine and rimantadine that was never marketed.[1][2][3] It was first described by 1978.[1]

Somantadine
Clinical data
Other namesPR 741-976; a,a-Dimethyl-1-adamantaneethylamine; [2-(1-Adamantyl)-1,1-dimethylethyl]amine
Identifiers
  • 1-(1-adamantyl)-2-methylpropan-2-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H25N
Molar mass207.361 g·mol−1
3D model (JSmol)
  • CC(C)(CC12CC3CC(C1)CC(C3)C2)N
  • InChI=1S/C14H25N/c1-13(2,15)9-14-6-10-3-11(7-14)5-12(4-10)8-14/h10-12H,3-9,15H2,1-2H3
  • Key:OWKXRDQRMTVCEX-UHFFFAOYSA-N

References

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  1. ^ a b Elks J (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. p. 2. ISBN 978-1-4757-2085-3. Retrieved 13 September 2024.
  2. ^ Milne GW (2017). Ashgate Handbook of Anti-Infective Agents: An International Guide to 1, 600 Drugs in Current Use: An International Guide to 1, 600 Drugs in Current Use. Routledge Revivals. Taylor & Francis. p. 294. ISBN 978-1-351-73490-5. Retrieved 13 September 2024.
  3. ^ Negwer M (1994). Organic-chemical Drugs and Their Synonyms: (an International Survey). Akademie Verlag. p. 943. ISBN 978-3-05-500156-7. Retrieved 13 September 2024.