This article may be too technical for most readers to understand.(April 2022) |
Thymidine monophosphate (TMP), also known as thymidylic acid (conjugate base thymidylate), deoxythymidine monophosphate (dTMP), or deoxythymidylic acid (conjugate base deoxythymidylate), is a nucleotide that is used as a monomer in DNA. It is an ester of phosphoric acid with the nucleoside thymidine. dTMP consists of a phosphate group, the pentose sugar deoxyribose, and the nucleobase thymine. Unlike the other deoxyribonucleotides, thymidine monophosphate often does not contain the "deoxy" prefix in its name; nevertheless, its symbol often includes a "d" ("dTMP").[1] Dorland’s Illustrated Medical Dictionary[2] provides an explanation of the nomenclature variation at its entry for thymidine.
Names | |
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IUPAC name
Thymidine monophosphate
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Other names
5'-Thymidylic acid
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Identifiers | |
3D model (JSmol)
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Abbreviations | dTMP |
3916216 | |
ChEBI | |
ChEMBL | |
ChemSpider | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C10H15N2O8P | |
Molar mass | 322.2085 g mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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As a substituent, it is called by the prefix thymidylyl-.
See also
editReferences
edit- ^ Coghill, Anne M.; Garson, Lorrin R., eds. (2006). The ACS style guide: effective communication of scientific information (3rd ed.). Washington, D.C.: American Chemical Society. p. 244. ISBN 978-0-8412-3999-9.
- ^ Elsevier, Dorland's Illustrated Medical Dictionary, Elsevier.