Envelysin (EC 3.4.24.12, sea-urchin-hatching proteinase, hatching enzyme, chorionase, chorion-digesting proteinase, chymostrypsin, sea urchin embryo hatching enzyme) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction

Envelysin
Identifiers
EC no.3.4.24.12
CAS no.50812-13-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
Hydrolysis of proteins of the fertilization envelope and dimethylcasein

This enzyme is a glycoprotein from various members of the class Echinoidea.

References

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  1. ^ Barrett D, Edwards BF (1976). "Hatching enzyme of the sea urchin Strongylocentrotus purpuratus". Part B: Proteolytic Enzymes. Methods in Enzymology. Vol. 45. pp. 354–73. doi:10.1016/s0076-6879(76)45032-2. ISBN 978-0-12-181945-3. PMID 1012003.
  2. ^ Lepage T, Gache C (March 1989). "Purification and characterization of the sea urchin embryo hatching enzyme". The Journal of Biological Chemistry. 264 (9): 4787–93. doi:10.1016/S0021-9258(18)83659-6. PMID 2925668.
  3. ^ Lepage T, Gache C (September 1990). "Early expression of a collagenase-like hatching enzyme gene in the sea urchin embryo". The EMBO Journal. 9 (9): 3003–12. doi:10.1002/j.1460-2075.1990.tb07493.x. PMC 552018. PMID 2167841.
  4. ^ Nomura K, Tanaka H, Kikkawa Y, Yamaguchi M, Suzuki N (June 1991). "The specificity of sea urchin hatching enzyme (envelysin) places it in the mammalian matrix metalloproteinase family". Biochemistry. 30 (25): 6115–23. doi:10.1021/bi00239a005. PMID 1711895.
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