William Ayres may refer to:
- William Ayres (cricketer) (1906–1978), South African cricketer
- William Augustus Ayres (1867–1952), Democratic member of the U.S. House of Representatives from Kansas
- William Hanes Ayres (1916–2000), Republican member of the U.S. House of Representatives from Ohio
- William Orville Ayres (1817–1887), American physician and ichthyologist
- Bill Ayers (born 1944), American professor and former radical
This disambiguation page lists articles about people with the same name.
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