Abraxis may refer to:

  • Abraxis BioScience, a wholly owned biopharmaceutical subsidiary of the biotechnology company Celgene
  • Abraxis, a fictional spacecraft, the primary setting for the animated film Dead Space: Aftermath
  • Creeper World 3: Abraxis, a video game in the Creeper World franchise
  • Abraxis, the name of the primary character in the Necropolis video game
  • Abraxis, an extra-dimensional being from the 1991–92 DC Comics storyline "Armageddon Inferno"
  • Abraxis, a 3-D-puzzle, 64 small cubes fixed to 13 parts combine to a 4x4x4 cube
  • Abraxis, a psy-trance trio formed by Seven Lions and Dimibo.

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