(−)-Isopiperitenone reductase (EC 1.3.1.82) is an enzyme with systematic name (+)-cis-isopulegone:NADP+ oxidoreductase.[1][2] It catalyses the following chemical reaction:
| (−)-isopiperitenone reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.3.1.82 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- (+)-cis-isopulegone + NADP+ (−)-isopiperitenone + NADPH + H+
The reaction occurs in the opposite direction.
References
edit- ^ Croteau R, Venkatachalam KV (September 1986). "Metabolism of monoterpenes: demonstration that (+)-cis-isopulegone, not piperitenone, is the key intermediate in the conversion of (-)-isopiperitenone to (+)-pulegone in peppermint (Mentha piperita)". Archives of Biochemistry and Biophysics. 249 (2): 306–15. doi:10.1016/0003-9861(86)90007-x. PMID 3755881.
- ^ Ringer KL, McConkey ME, Davis EM, Rushing GW, Croteau R (October 2003). "Monoterpene double-bond reductases of the (-)-menthol biosynthetic pathway: isolation and characterization of cDNAs encoding (-)-isopiperitenone reductase and (+)-pulegone reductase of peppermint". Archives of Biochemistry and Biophysics. 418 (1): 80–92. doi:10.1016/s0003-9861(03)00390-4. PMID 13679086.
External links
edit- (−)-isopiperitenone+reductase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
