Sushko (Russian: Сушко) is a gender-neutral Slavic surname that may refer to
- Hennadiy Sushko (born 1970), Ukrainian football coach and former player
- Iryna Sushko (born 1967), Ukrainian mathematician
- Maxim Sushko (born 1999), Belarusian ice hockey forward
- Orest Sushko, re-recording film mixer
- Pavlo Sushko (born 1979). Ukrainian politician
- Vadim Sushko (born 1986), Belarusian ice hockey defenceman
- Yuriy Sushko (born 1979), Ukrainian serial killer